Insular system of animals in a chronic heparin deficiency
Ul'ianov, A.M.; Tarasov, I.A.
Voprosy Meditsinskoi Khimii 46(2): 149-154
2000
ISSN/ISBN: 0042-8809 PMID: 10885035 Document Number: 515327
The chronic heparin deficiency achieved by long-term treatment (for 3 weeks) with protamine-sulfate is accompanied by the development of stable hyperglycemia, decreased glucose tolerance, and the appearance of insulin resistance. Administration of exogenous heparin promotes the restoration of normoglycemia.
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