Utilization of aortomyoplasty as a biological pumping system
Chachques, J.C.; Braunberger, E.; Latrémouille, C.; Lajos, P.; Meimoun, P.; Fabiani, J.N.; Carpentier, A.
Archives des Maladies du Coeur et des Vaisseaux 93(7): 849-855
2000
ISSN/ISBN: 0003-9683 PMID: 10975037 Document Number: 514241
Aortomyoplasty is a surgical technique of constructing a neo-ventricle on the ascending or descending aorta with the latissimus dorsi muscle. This is electrically stimulated to contract during diastole, thereby creating a system of chronic, haemo-compatible aortic pumping. Long-term experimental studies have shown increases in cardiac output (from 3.6 to 5.5 l/min), decreases in peripheral resistances (from 1574 to 1134 dyne.sec.cm-5) and increases in indices of subendocardial viability (DPTI/TTI: 1.1 to 1.4). These experimental studies have been confirmed by the initial clinical results. To date, world experience includes thirty-six patients. With cardiomyoplasty, aortomyoplasty is a new arm in the therapeutic arsenal against severe cardiac failure by providing a new system of chronic circulatory assistance which is implantable and biocompatible.