Genetic prediction in medicine
Feingold, J.
Gynecologie Obstetrique and Fertilite 28(5): 391-395
2000
ISSN/ISBN: 1297-9589 PMID: 10893883 Document Number: 513719
Presymptomatic or predictive genetic testing concerns healthy people. Its aim is to determine individuals at risk for a disease. Presymptomatic testing concerns mainly Mendelian diseases; an abnormal test result will lead to development of the disease in most cases in later life. Predictive testing concerns multifactorial or low penetrating Mendelian diseases; the test result will modify the risk of disorder occurring but with a much smaller degree of certainty.