A study of the liver glucocorticoid receptor binding capacity in newborn rat
Csaba, G.; Inczefi-Gonda, A.
Acta Physiologica Hungarica 87(2): 139-143
2000
ISSN/ISBN: 0231-424X PMID: 11205961 Document Number: 513670
The binding capacity of newborn and adult rat liver glucocorticoid receptors was compared, using receptor kinetic analysis. Neonatal receptors have (non-significantly) lower affinity and significantly less density to dexamethasone than adult ones. However, the neonatal binding is specific and there is no qualitative difference from the adult one.
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