Drug treatment for the treatment of primary osteoporosis
Halbekath, J.
Zeitschrift für Arztliche Fortbildung und Qualitatssicherung 94(6): 453-460
2000
ISSN/ISBN: 1431-7621 PMID: 10996934 Document Number: 513082
The goal of drug treatment of osteoporosis is to prevent fractures. Increase of bone density during therapy is not consistently associated with a clinical benefit. The purpose of this paper is to review the evidence of fracture prevention from published randomized controlled trials. Vitamin D, the bisphosphonate alendronate and the selective estrogen receptor modulator raloxifene have been evaluated in large randomized trials with clinical endpoints.