Preparation, evaluation of specificity and use of anti-le monoclonal antibodies
Lapenkov, M.I.; Nikolaeva, T.L.; Aborina, E.A.
Sudebno-Meditsinskaia Ekspertiza 43(4): 25-29
2000
ISSN/ISBN: 0039-4521 PMID: 10961130 Document Number: 512930
Anti-Le(a) and anti-Le(b) monoclonal antibodies were obtained and attempts at evaluating their epitope specificity have been made. A method for identification of Lewis phenotypes in salivary specimens by dot-I enzyme immunoassay has been developed. Analyses of salivary samples from 72 donors detected donors with phenotypes Le(a-b-) and Le(a+b+), which was confirmed by hemagglutination test.
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