Use of native and lyophilized Loewenstein-Jensen&apos;s solid media in determining drug resistance on mycobacterium tuberculosis strains

Korneev, A.A.; Golyshevskaia, V.I.; Sevast'ianova, E.V.; Safonova, S.G.; Puzanov, V.A.; Maslennikova, I.V.; Katulina, N.I.; Stoiunin, M.B.; Korneev, A.A; Golyshevskaia, V.I; Sevast&apo; ianova, E.V; Safonova, S.G; Puzanov, V.A; Maslennikova, I.V; Katulina, N.I; Stoiunin, M.B

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Use of native and lyophilized Loewenstein-Jensen's solid media in determining drug resistance on mycobacterium tuberculosis strains

Korneev, A.A.; Golyshevskaia, V.I.; Sevast'ianova, E.V.; Safonova, S.G.; Puzanov, V.A.; Maslennikova, I.V.; Katulina, N.I.; Stoiunin, M.B.

Problemy Tuberkuleza 4: 25-27

1999

ISSN/ISBN: 0032-9533

PMID: 10479928

Document Number: 510287

The results of determination of drug medium depend on both individual cultural properties of the strains tested and the type of the medium used. The composition of a medium is of significance for some strains: the latter grow in any medium and are characterized by the same spectrum of resistance. However, most drug-resistant strains have higher feeding demands which are not fully met on the lyophilized Löwenstein-Jensen medium. The strains in the lyophilized medium show an incomplete spectrum of resistance and less grow than do those in freshly prepared Löwenstein-Yersen medium.