Sweet's syndrome with arthritis in an 8-month-old boy
Tuerlinckx, D.; Bodart, E.; Despontin, K.; Boutsen, Y.; Godding, V.; Ninane, J.
Journal of Rheumatology 26(2): 440-442
1999
ISSN/ISBN: 0315-162X PMID: 9972982 Document Number: 509962
Sweet's syndrome was diagnosed in a 4-month-old boy. He was successfully treated with systemic corticosteroids. At the age of 8 months, he developed acute arthritis in his right knee. The synovial fluid was analyzed and revealed a very high neutrophil count and neutrophil activation with a detectable level of intraarticular granulocyte-monocyte colony stimulating factor (GM-CSF). Prednisone injection into the knee led to dramatic improvement. No recurrence occurred. Although arthritis and/or arthralgia are common features in adult patients with Sweet's syndrome, this is the first reported case of Sweet's arthritis in a child.