Growth behavior of cells of ameloblastoma and odontogenic keratocyst
Zhao, N.; Yu, S.; Wang, W.
Zhonghua Kou Qiang Yi Xue Za Zhi 34(1): 31-33
1999
ISSN/ISBN: 1002-0098 PMID: 11776531 Document Number: 509845
To compare the growth behavior of epithelium and fibroblast from ameloblastoma and keratocyst and to discuss the recurrence reason for the keratocyst. Epithelial cells and fibroblast from ameloblastoma, keratocyst, dentigerous cyst, radicular cyst and oral mucosa were cultured and observed by phase-contrast microscope. The epithelial cells of ameloblastoma grew faster, with an irregular area around the cell mass and some small satellite-shaped cell mass. The epithelial cells of all the cysts and mucosa grew slower with the cell masses surrounded by fibroblasts which grew in whirl manner with a round and smooth periphery. The cells from the ameloblastoma grow faster and more active, and those from the keratocysts grow like the other cysts and the normal mucosa. It is speculated that the ameloblastoma grows in an aggressive manner and it is possible that the recurrence of the keratocyst isn't primarily resulted from its growth behavior as a tumor.