Elastase imbalance: alpha-1 antitrypsin in aneurysms
Lisowska-Myjak, B.
Neurologia i Neurochirurgia Polska 33(1): 143-149
1999
ISSN/ISBN: 0028-3843 PMID: 10399732 Document Number: 509769
The balance between proteinases and their inhibitors is important in maintaining structural integrity of connective tissues, including the arterial wall. Elevated serum elastase level is a possible serum marker of patients with high risk of aneurysm formation. Possibly, the heterozygous and the homozygous AAT deficiency states are genetic risk factors that could predispose a aneurysm formation.
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