Ochronotic arthritis of knee
Muralikuttan, K.P.; Punnose, J.; Joshi, S.; Sankaran-Kutty, M.
Saudi Medical Journal 20(4): 316-318
1999
ISSN/ISBN: 0379-5284 PMID: 27614492 Document Number: 509250
Ochronotic arthropathy of the knee is a common manifestation of alkaptonuria and may present before symptoms of spondylitis. The joint disease can be rapidly progressive and crippling, necessitating early total joint replacement. The clinical features of this inborn error of metabolism are often overlooked and hence remain undiagnosed until the onset of spondyloarthropathy.