Human type 6, 7, and 8 herpesviruses--new pathogens in the Herpesviridae family
L'vov, N.D.; Mel'nichenko, A.V.
Voprosy Virusologii 44(3): 105-111
1999
ISSN/ISBN: 0507-4088 PMID: 10392432 Document Number: 508287
Presents modern data on a group of novel viruses pathogenic for man: types 6, 7, and 8 human lymphotropic herpesviruses (HHV-6, HHV-7, and HHV-8). HHV-6 and HHV-8 are characterized by wide cell tropism, and HHV-7 is selectively tropic to CD4+ T-lymphocytes. HHV-6 and HHV-7 are etiological agents of exanthema subitum (roseoia infantum), a disease of infancy, and of many grave lymphoproliferative disorders, and HHV-8 is a herpesvirus associated with Kaposi's sarcoma. The morphology, immunobiology, pathogenesis, clinical picture, epidemiology, and therapy of HHV, HHV-7, and HHV-8 infection are characterized in brief.