Detection of bilateral multifocal breast cancer using Tc-99m sestamibi imaging. The role of delayed imaging
Derebek, E.; Balci, P.; Alanyali, H.; Kocdor, M.A.; Capa, G.; Gorken, I.B.; Degirmenci, B.; Alakavuklar, M.; Canda, T.; Durak, H.
Clinical Nuclear Medicine 24(8): 590-593
1999
ISSN/ISBN: 0363-9762 PMID: 10439180 Document Number: 507094
Purpose: Early determination that breast cancer is bilateral and multifocal can change therapy strategy and, subsequently, mortality and morbidity rates. The authors present a case with bilateral, multifocal breast cancer detected only by Tc-99m sestamibi imaging. Methods: Early and delayed Tc-99m sestamibi imaging and dynamic MRI were performed in a patient with a right-sided lesion shown on mammography. Results: Although early Tc-99m sestamibi imaging detected bilateral breast cancer foci, both dynamic MRI and mammography missed the lesion in the left breast. Additional lesions seen on delayed Tc-99m sestamibi images of the left breast, which were initially thought to be benign, completely disappeared after concomitant chemotherapy and radiotherapy, suggesting multifocal malignant lesions in the left breast. Conclusion: This case suggests that Tc-99m sestamibi may be useful for detecting bilateral cancer, and delayed imaging may give additional information regarding the possible multifocal nature of the disease.