Long-lasting neuropsychiatric side-effects following mefloquine prophylaxis. a case after six weeks of initiating and lasting six months
Bygbjerg, I.C.; Rønn, A.M.
Ugeskrift for Laeger 161(10): 1422-1423
1999
ISSN/ISBN: 0041-5782 PMID: 10085752 Document Number: 506699
Neuropsychiatric side-effects from mefloquine are well known. When used for prophylaxis, the side-effects have been claimed to be relatively rare, mild and transient, most often arising within two to three weeks, and in patients with a previous history of neuropsychiatric disorders. We here describe a case of severe neuropsychiatric side-effects arising six weeks after initiating mefloquine prophylaxis, requiring repeated hospitalization, and not resolving completely after six months, in a previously healthy 30 year-old female.