Gougerot-Sjögren syndrome. Neurologic complications
Amoura, Z.; Lafitte, C.; Piette, J.C.
Presse Medicale 28(22): 1209-1213
1999
ISSN/ISBN: 0755-4982 PMID: 10414251 Document Number: 503402
PERIPHERAL NERVE INVOLVEMENT: Peripheral nerve involvement is better known than central nervous system involvement. The dominant features are sensoromotor polyneuropathies or pure sensorial polyneuropathies. CENTRAL NERVOUS SYSTEM: The manifestations are polymorphous, generally presenting as encephalitis and/or focal or multifocal involvement of the spinal cord. OTHER LOCALIZATIONS: Diffuse encephalic involvement is less common: acute aseptic meningitis, intellectual deterioration. Psychiatric manifestations are also frequently observed. Response to corticosteroid therapy or immunosuppressor therapy can be spectacular but is unpredictable.