The neurons of the medial vestibular nucleus initiating the relaxation of the rat's stomach wall
Panteleev, S.S.; Aleksandrov, V.G.; Bagaev, V.A.; Busygina, I.I.; Liubashina, O.A.
Aviakosmicheskaia i Ekologicheskaia Meditsina 33(2): 15-19
1999
ISSN/ISBN: 0233-528X PMID: 10399549 Document Number: 502786
In acute rat experiments the technique of retrograde axonal transport of horseradish peroxidase in the medial vestibular nucleus allowed to identify a group of neurones sending axons to the "stomach" region of a single tract nucleus. These neurones and, accordingly, the descending vestibular/solitary links can be viewed as the morphologic basis for vestibular influences on the gastric motor activity. As was shown, local irritation of the neurones initiates relaxation of the stomach wall. Activation of the anterior limbic cortex modulates the vestibular/autonomous responses of the intragastric pressure reduction. Irritation of the infralimbic cortex of the rat's brain may have a preventive effect on the stomach wall relaxation stimulated by the vestibular neurones projecting on the "stomach" region of single tract nucleus.