The effect of carbon dioxide pneumoperitoneum on the portal hemodynamics in a portal-hypertensive rat model
Tsugawa, K.; Hashizume, M.; Migou, S.; Tanoue, K.; Kishihara, F.; Kawanaka, H.; Sugimachi, K.
Surgical Laparoscopy Endoscopy and Percutaneous Techniques 9(5): 338-347
1999
ISSN/ISBN: 1530-4515 PMID: 10803396 Document Number: 502350
As use of laparoscopic surgery grows, various complications with pneumoperitoneum have been reported. However, there are no reports on the relation between the carbon dioxide (Co2) pneumoperitoneum and portal hemodynamics. The purpose of this study was to determine how the pneumoperitoneum affects the portal hypertensive state. Portal-hypertensive rats, control rats, and sham operation rats were studied. The mean arterial pressure, portal venous pressure, central venous pressure, red blood flow volume of the viscera, and liver and renal function were investigated. The findings of this study suggest that Co2 pneumoperitoneum at less than 10 mm Hg does not present any undue risk to the portal hemodynamics in portal-hypertensive rats; however, more attention should be paid to the IAP in PHT patients undergoing surgery.