Hepatoprotective activity of ellagic acid against carbon tetrachloride induced hepatotoxicity in rats
Singh, K.; Khanna, A.K.; Chander, R.
Indian Journal of Experimental Biology 37(10): 1025-1026
1999
ISSN/ISBN: 0019-5189 PMID: 10783760 Document Number: 501818
Administration of CCl4 to normal rats and consequent oral feeding with ellagic acid (50 mg/kg) provided a significant protection against the biochemical alterations in serum and liver produced by CCl4. In vitro experiments showed that liver microsomes from animals treated with ellagic acid and CCl4, decreased lipid peroxidation compared to microsome prepared from rats exposed to CCl4 alone.
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