Synthesis of inositol phosphates and phospholipids
Watanabe, Y.
Anticancer Research 19(5a): 3727-3732
1999
ISSN/ISBN: 0250-7005 PMID: 10625948 Document Number: 499582
Inositol phospholipids and their hydrolysis products have been recognized to play important roles in an intracellular signal transduction system. Since their contents in cells are quite low, synthetic methods for their production are required. Chemical synthesis of various inositol phosphates and inositol phospholipids, including natural phosphatidylinositol 3,4,5-trisphosphate, have been efficiently accomplished. For this purpose, several new reactions and reagents were developed.
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