Diisocyanates in polyurethane plastics applications
Klees, J.E.; Ott, M.G.
Occupational Medicine 14(4): 759-776
1999
ISSN/ISBN: 0885-114X PMID: 10495484 Document Number: 499506
Diisocyanates are a group of low molecular weight aromatic and aliphatic compounds, widely used in the manufacture of polyurethanes. The most commonly used of these compounds are toluene diisocyanate (TDI), methylene diphenyl diisocyanate (MDI), and hexamethylene diisocyanate (HDI). This article presents a brief summary of the use of diisocyanates in the manufacture of polyurethane products and a review of the epidemiology, medical surveillance, and clinical diagnosis of respiratory and dermal effects of diisocyanates, with emphasis on diisocyanate asthma.