Heparin inhalations combined with intravenous laser exposure of blood in patients with diabetic retinopathy
Balashova, L.M.; Teplinskaia, L.E.; Zaĭtseva, N.S.; Efimov, V.S.; Grishin, V.L.; Bibilashvili, R.S.; Belogurov, A.A.
Vestnik Oftalmologii 115(1): 16-18
1999
ISSN/ISBN: 0042-465X PMID: 10207313 Document Number: 498453
Heparin inhalations combined with intravenous laser exposure of the blood are effective in patients with nonproliferative, preproliferative, and proliferative diabetic retinopathy. Clinical effect consisted in decrease of edema in the macular area, partial resolution of hemorrhages, a tendency to decrease in the caliber of veins, improvement of visual acuity, and extension of visual field. Immunological studies revealed immunomodulating effect of heparin inhalations and intravenous laser exposure of the blood, manifesting by decreased levels of pathological circulating immune complexes and increased concentrations of immunoglobulins, mainly IgG and IgM. Diabetic hemophthalmia is to be treated by subtenon implantation of a collagen system with injection of a prourokinase thrombolytic in combination with preoperative preparation including heparin inhalations, intravenous laser exposure of the blood, and parabulbar administration of 0.5 ml 1% emoxipin for 5 days in order to normalize immune hemostatic and redox processes and create conditions for effective action of the thrombolytic.