Arterial calcification. Mechanisms, consequences and animal models
Atkinson, J.
Pathologie-Biologie 47(7): 677-684
1999
ISSN/ISBN: 0369-8114 PMID: 10522258 Document Number: 498154
The arterial extracellular matrix undergoes many profound age-related changes leading to an increase in wall stiffness. In this review the evidence suggesting that calcium - and more importantly "calcification" of elastin fibres - is involved in the age-related increase in arterial stiffness is examined.
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