High pressure technology and examples of its use in the biological sciences
Kamarád, J.; Cepelková, M.
Sbornik Lekarsky 99(4): 529-538
1998
ISSN/ISBN: 0036-5327 PMID: 10803297 Document Number: 497662
A short description of basic types of high pressure apparatuses is presented in view of their application in a research in the biosciences. General tendencies in an evolution of characteristic inter-atomic bonds and their changes under high pressure are shortly reviewed. A complex behaviour of organic macromolecular compounds under pressure is demonstrated by the effects of pressure on proteins (including p--T diagram of proteins denaturation). In consequence, an effect of pressure on the simplest micro-organisms is mentioned and relevant critical pressures of sterilization are presented. Trends in a future application of results of the pressure research in biosciences are discussed.