Biological calculation methods and their application in pharmaceutical science
Massart, D.L.
Verhandelingen - Koninklijke Academie Voor Geneeskunde van Belgie 60(6) 535-564; Discussion: 564-565
1998
ISSN/ISBN: 0302-6469 PMID: 10230324 Document Number: 497197
This article gives an introduction to certain mathematical methods, that were developed with biological processes as model. Three methods are described: clustering and the more recently developed genetic algorithms and neural nets. Mainly the last two methods were applied first outside the medical and biological domain but are now used also in the medical and pharmaceutical sciences. There are many applications in the drug discovery field, but these methods are also becoming increasingly important in other domains of the pharmaceutical sciences (such as pharmaceutical technologies).