Xenoestrogens, pollution and health: a critical review

Gozzo, F.; Poupaert, J.H.

Journal de Pharmacie de Belgique 53(4): 278-286

1998


ISSN/ISBN: 0047-2166
PMID: 9766095
Document Number: 496657
This review article provides basic information concerning the xenoestrogens (i.e. the sexual hormone mimetic or disruptive compounds) in a perspective willingly selective of the recent literature. In the second part, a hypothetical link between xenoestrogens and disturbances of the central nervous system is considered with respect to steroids more directly involved in the CNS, i.e. the neurosteroids. The data accumulated so far on xenoestrogens present in the environment and their possible competition for membrane-bound neurosteroid receptor sites lend support to the working hypothesis that human behaviour could be affected in the daily life by exposure to chemical pollutants.

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