Pharmacokinetics of beta blockers in hyperthyroidism. Therapeutic relevance
Bouvier, N.; Millart, H.
Therapie 53(6): 523-531
1998
ISSN/ISBN: 0040-5957 PMID: 10070229 Document Number: 495175
Hyperthyroidism is associated with alterations in pharmacokinetic parameters such as absorption, distribution, metabolism and elimination. Beta-blockers are used in particular in the treatment of hyperthyroidism and are also subject to pharmacokinetic changes occurring during this pathology. The magnitude of these variations is examined when beta-blockers are used for clinical manifestations of hyperthyroidism or during thyroid surgery. Clinical means used to assess the accuracy of therapeutic drug monitoring are also described.