Changes on the Temperament and Character Inventory after paroxetine treatment in volunteers with generalized anxiety disorder
Allgulander, C.; Cloninger, C.R.; Przybeck, T.R.; Brandt, L.
Psychopharmacology Bulletin 34(2): 165-166
1998
ISSN/ISBN: 0048-5764 PMID: 9640994 Document Number: 493667
Previously untreated symptomatic volunteers with generalized anxiety disorder (GAD) performed the Temperament and Character Inventory at baseline and after 4 to 6 months of paroxetine treatment. Scores from 29 volunteers were analyzed with paired t-tests. A marked reduction was noted in Harm Avoidance and a marked increase was noted in Self-Directedness. Smaller changes were noted in Cooperativeness and Novelty Seeking. Overall, treatment was associated with a reduction in maladaptive personality traits.