Reversible left intraventricular obstruction after treatment of pheochromocytoma and hyperthyroidism
Gandolfini, M.P.; Lefrançois, A.M.; Pannier-Moreau, I.; Guiomard, A.
Archives des Maladies du Coeur et des Vaisseaux 91(12): 1513-1518
1998
ISSN/ISBN: 0003-9683 PMID: 9891836 Document Number: 492821
The authors report an original case of the association of three pathologies: pheochromocytoma, hyperthyroidism and cardiomyopathy with left ventricular outflow tract obstruction. This type of cardiac disease has occasionally been described in cases of pheochromocytoma and are usually induced by the endocrine disturbance because they regress with treatment of the pheochromocytoma. The associated hyperthyroidism observed in this case is very rare and may have increased the left ventricular pressure gradient. Medical treatment before surgery of the pheochromocytoma was unusual in that a triple therapy was used including betablockers, classically contra-indicated in pheochromocytoma alone. In this case, it provided excellent control of the blood pressure and decreased the left ventricular obstruction during the perioperative period.