Values of phase-contrast microscopy in the etiological diagnosis of hematuria in adults. Part I. Establishing individual norms for glomerular hematuria
Obroniecka, I.
Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego 5(29): 277-279
1998
ISSN/ISBN: 1426-9686 PMID: 10101500 Document Number: 492214
In the cohort of 123 patients (average age 44 years) criteria for glomerular and nonglomerular hematuria (H) were established by phase-contrast microscopy (PCM). According to literature, hematuria was divided into glomerular, mixed or nonglomerular if: > 60%, 20-60% and < 20% dysmorphic erythrocytes (E) of fresh morning urine sediment were found. Diagnosis of glomerulonephritis was confirmed by renal biopsy in 54/57 glomerular H as well as in all 8 cases of mixed H. On the contrary, urological reasons for H were found in 55/58 cases of nonglomerular H with normal renal biopsy in the remaining 3 patients. Using value > 20% of dysmorphic E as a new norm for glomerular H, we found sensitivity and specificity of this test as 100% and 95% respectively. glomerular H should be suspected and renal biopsy recommended when > 20% dysmorphic E are found by PCM what means exclusion of the term "mixed H".