General anesthesia in a patient with Cornelia de Lange syndrome with restricted opening of the mouth
Yo, T.; Noguchi, I.; Kimura, T.; Sasao, M.; Amemiya, Y.; Sekiya, H.; Kobayashi, K.
Masui. Japanese Journal of Anesthesiology 47(5): 611-614
1998
ISSN/ISBN: 0021-4892 PMID: 9621675 Document Number: 492130
Patients with Cornelia de Lange syndrome have many anomalies including micrognathia with a small mouth, a high arched palate, and a short neck, which might make laryngoscopy for tracheal intubation difficult during induction of general anesthesia. General anesthesia was performed in a patient with Cornelia de Lange syndrome, and restricted opening of the mouth, which had not been reported previously, was found during laryngoscopy. The possible causes were thought to be temporo-mandibular joint disorders, contracture of the masseter muscle due to injury by self-destructive tendencies, or elongated coronoid process. The potential difficulty with laryngoscopy should be considered for tracheal intubation in a patient with Cornelia de Lange syndrome.