A preclinical trial of iodoantipyrine safety
Saratikov, A.S.; Novozheeva, T.P.; Livshits, N.S.; Burchenkova, F.I.; Kadychagova, N.G.; Akhmedzhanov, R.R.; Bashirova, L.V.; Eremina, A.A.; Potapova, G.V.
Eksperimental'naia i Klinicheskaia Farmakologiia 61(2): 57-59
1998
ISSN/ISBN: 0869-2092 PMID: 9621178 Document Number: 490570
Detailed preclinical study of the safety of the new antiviral agent iodantipyrine was conducted. In LD50 parameters it was found to be related to moderately toxic drugs. Long-term administration in doses of 50, 100, and 250 mg/kg did not cause any essential functional and structural disorders in the organs and systems of rats and dogs. Iodantipyrine does not possess mutagenic and allergenic properties and does not affect the reproductive function.
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