Study on the power of O/E method
Wu, Y.; Chen, F.; Kang, C.; Yang, S.
Hua Xi Yi Ke da Xue Xue Bao 29(1): 66-69
1998
ISSN/ISBN: 0257-7712 PMID: 10683984 Document Number: 489221
This paper addresses the methodology of calculating the power of O/E method and introduces the relevant algorithm for estimating the sample size. Based on the principles of hyporthesis testing and Poisson distribution, the power can be worked out for given sample size, baseline rate(pi 0) and the factor of increasing (gamma). The power increases with the increase in sample size, pi 0 and gamma. In shape the power is not a continuous smooth line but a zigzag line. The method illustrated in this paper can be also used for estimaging the sample size of studies on the intervention of diseases.