Hemodynamics and oxygen transport in patients with surgical sepsis during hemofiltration
Bobrinskaia, I.G.; Tishkov, E.A.; Bukaev, O.B.; Kapunov, S.V.; Konstantinov, V.V.; Smolenenkova, S.V.
Anesteziologiia i Reanimatologiia 6: 58-62
1998
ISSN/ISBN: 0201-7563 PMID: 10050340 Document Number: 488647
Effects of hemofiltration (HF) on central hemodynamics and oxygen transport are studied in 35 patients with surgical sepsis and multiple organ failure. HF is paralleled by development of hypovolemia and decrease of myocardial contractility, determining a decrease in cardiac output and oxygen transport. As a result, oxygen utilization by tissues decreases and hypoxia progresses. The only compensatory mechanism of oxygen supply in such patients is maintenance of cardiac output, which should be borne in mind when carrying out HF.