Drug-induced hepatic injuries
Spigset, O.
Tidsskrift for den Norske Laegeforening Tidsskrift for Praktisk Medicin Ny Raekke 118(18): 2805-2808
1998
ISSN/ISBN: 0029-2001 PMID: 9748813 Document Number: 487353
This article provides a survey on various aspects of drug-induced hepatic dysfunction, including practical considerations for handling patients with suspected drug-induced liver affection. The assessment of causality is discussed on the basis of liver enzyme abnormalities, the onset and course of the reaction, and the response to readministration of the drug. Issues on when to withdraw a suspected drug and how to prescribe potentially hepatotoxic drugs to patients with liver diseases are also presented.