Measurement of forces between biomolecules by atomic force microscopy
Zhang, Y.G.; Wang, C.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 15(4): 424-428
1998
ISSN/ISBN: 1001-5515 PMID: 12552794 Document Number: 486029
The intermolecular forces of the biological samples may be measured by atomic force microscopy, which has provided a powerful means for us to understand the principles of living phenomena. Some systems in which the interaction forces between biomolecules have been measured hitherto include: 1. ligand-receptor; 2. actin-myosin; 3. proteoglycans; 4. DNA complementary strands and nucleotides; 5. special organic chemical groups. A literature review on these objects is presented in this article.