Augmentation strategies with serotonergic-noradrenergic combinations
Nelson, J.C.
Journal of Clinical Psychiatry 59(Suppl): 65-68
1998
ISSN/ISBN: 0160-6689 PMID: 9635550 Document Number: 484647
Combinations of antidepressants with both serotonergic and noradrenergic activity may be especially effective and thus useful in treating refractory patients and severely depressed patients. In the current report, studies of combinations of serotonin selective reuptake inhibitors (SSRIs) and noradrenergic tricyclics or of SSRIs and bupropion are reviewed, and practical issues pertaining to their use are discussed.
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