The immunological and morphological aspects of chronic hepatitis caused by HBV
Gabriel, A.; Szczurek, Z.; Ziółkowski, A.; Pawłowski, S.
Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego 4(23): 292-294
1998
ISSN/ISBN: 1426-9686 PMID: 9825667 Document Number: 484242
The authors present in the study actual knowledge of the pathogenesis of the chronic viral hepatitis type B. Dividing of the disease into stages with description immunologic reactions connected with morphological features of the liver is used. Three stages of the disease have been reported: replication, elimination and integration of HBV in the liver. It present the results of immunohistological analysis of the incidence of the virus antigen in the tissue in the particular stages of the disease. Next it explains the mechanisms of immunological reaction leading to the incidence of particular forms of the inflammation activity and types of necrosis that occur in the chronic viral hepatitis type B.