Comparison of HIV-1 envelope-specific CD4+ T cell lines simultaneously established from peripheral blood mononuclear cells and lymph node biopsy in HIV-1-infected individuals
Ratto-Kim, S.; Sitz, K.V.; Scherer, A.M.; Kim, J.H.; Anderson, D.W.; Nau, M.E.; Mann, D.L.; Akolkar, P.N.; Gulwani-Akolkar, B.; Silver, J.; Birx, D.L.
Journal of Immunology 159(10): 5162-5167
1997
ISSN/ISBN: 0022-1767 PMID: 9366447 Document Number: 483932
These data suggest that the cellular immune response does not phenotypically vary between the peripheral blood and lymph node compartments, but demonstrates genotypic heterogeneity, showing possible redundancy of the immune response to HIV-1 gp160.
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