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Topical progesterone as support for the luteal phase in induced cycles

Zaffaroni, L.; Costa, P.; Vinci, G.W.

Minerva Ginecologica 49(7-8): 361-364

1997

ISSN/ISBN: 0026-4784
PMID: 9380299
Document Number: 481942
e efficacy and tolerability of 2.5% natural vaginal progesterone as luteal phase support in pharmacologically induced cycles has been evaluated. On the basis of the administered therapy, the population studied was subdivided at random into four different groups. Sixty patients came to the Sterility Autonomous Department of the Niguarda Ca' Granda Hospital in Milan from November 1994 to January 1996. Both ultrasonographic and plasmatic hormonal parameters have been evaluated on a monthly basis. The plasma progesterone levels and ultrasonographic endometrial thickness average values resulted more important in groups treated with topical progesterone; in these same groups a greater percentage of pregnancies was observed. The results obtained demonstrated that the drug studied can be recommended as a valid luteal phase support in pharmacologically induced cycles.

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