In vivo investigations of stress susceptibility in pigs by means of magnetic resonance spectroscopy
Kallweit, E.; Baulain, U.; Henning, M.; Kohn, G.
Deutsche Tierärztliche Wochenschrift 104(9): 380-383
1997
ISSN/ISBN: 0341-6593 PMID: 9410728 Document Number: 481161
31P nuclear magnetic resonance spectroscopy was performed on 19 to 55 kg weighing pigs of different MHS genotypes to study the changes of phosphorus components (inorganic phosphate - Pi, phosphocreatine - PCr and adenosine triphosphate - ATP) of muscle metabolism as well as intramuscular pH under application of halothane. Aim of the present study was to observe the changes in energy metabolism and to perform a comparison with also measured blood parameters. Both, NN and Nn pigs did not show any changes during halothane exposure in phosphorus spectra, but in all animals a partially metabolicly compensated respiratoric acidosis was found. In all MHS positive pigs a rapid fall of PCr and a corresponding raise of Pi levels in muscle was observed.