Change in distribution of actin and intermediate filaments at early stages of action of epidermal growth factor on A431 cells
Bobrova, I.F.; Teslenko, L.V.; Korolev, E.V.
Tsitologiia 39(11): 1063-1069
1997
ISSN/ISBN: 0041-3771 PMID: 9505349 Document Number: 480531
By electron microscopy using immunocytochemical reactions on actin and EGF-R with mild glycerinization it became possible to reveal a thick layer of actin filaments under the apical membrane within the first minutes of the impact of EGF on A431 cells. Keratin fibrils being located near the nucleus are transported apart from the membrane. It is supposed that this process is connected with retardation of capping on principles of competition.
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