Role of redchilli (Capsaicin) in the formation of colonic carcinoma

Chitra, S.; Viswanathan, P.; Nalini, N.; Sabitha, K.; Menon, V.P.

Indian Journal of Pathology and Microbiology 40(1): 21-25

1997


ISSN/ISBN: 0377-4929
PMID: 9145607
Document Number: 480179
The effect of feeding redchilli (Capsaicin) powder on the histopathological changes occurring in the colonic mucosa was studied in rats. These animals were compared with those treated with a colonic carcinogen 1,2-dimethylhydrazine (DMH). Animals fed with redchilli, dimethylhydrazine, dimethylhydrazine plus redchilli powder showed polyp and dysplasia, malignant tumour and malignant tumour with transitional area of dysplasia.

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