Further Studies of Enovid in the Treatment of Psychiatric Patients
Simpson, G.M.; Rochlin, D.; Kline, N.S.
Diseases of the Nervous System 25: 484-486
1964
ISSN/ISBN: 0012-3714 PMID: 14199196 Document Number: 479061
Administration of Enovid (30 mg daily) resulted in a difference of response in 2 groups of hospitalized psychotic patients: regularly menstruating patients (13) compared to irregularly or non-menstruating patients (12). All 4 patients who improved were in the regularly menstruating group. Breakthrough bleeding occurred in 7 of the 25 patients, and 6 of these 7 patients were in the regularly menstruating group. The incidence of side effects and the significance of these findings is briefly discussed.