Low dosage gestagens in fertility control
Osman, E.; Foda, M.S.; Darwish, N.A.; Kahil, S.A.; Wassef, S.A.
Egyptian Population and Family Planning Review 3(1): 95-106
1970
ISSN/ISBN: 1110-1156 PMID: 12254512 Document Number: 478778
A clinical study of a daily dosage of .5 chlormadinone acetate, a progestagen, was carried out on 101 randomly chosen women for a total of 954 cycles in Galaa Hospital and in the University Hospital Mansoura Faculty of Medicine. There were no reportedly pregnancies. One patient discontinued use after 16 days because of continuous bleeding. There were 20 dropouts between cycles 1-8 with reasons not investigated. Minor side effects included headache, giddiness, nausea, distension and breast discomfort. Of 34 lactating women in the study, 32 reported no effect on lactation and 2 reported diminished lactation. Amenorrhea was reported in 10% of the cycles. Cervicle mucus studies showed the mucus to be hostile to sperm.