Pulmonary metastases in metastatic prostate cancer: host tissue-tumor cell interactions and response to hormone therapy
Behrakis, P.; Koutsilieris, M.
Anticancer Research 17(3a): 1517-1518
1997
ISSN/ISBN: 0250-7005 PMID: 9179189 Document Number: 478558
Stage D2 prostate cancer patients with pulmonary metastases and absence of detectable metastases in bones are quite rare and almost always show accompanying favorable and long-term clinical response to hormone therapy. We present a case of a patient with pulmonary metastases caused by prostate cancer who experienced 13-year complete clinical response to GnRH analogues and we discuss the possible implications of host tissue-metastatic cancer cell interactions in pulmonary metastases and clinical response to hormone depletion therapy.