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Immunologic bases of graft vs. host disease: 1997

Uher, F.

Orvosi Hetilap 138(35): 2163-2168

1997

ISSN/ISBN: 0030-6002
PMID: 9324676
Document Number: 478185
The development of a graft-versus-host reaction after hematopoietic stem cell transplantation is an important determinant of the transplant outcome. The existence of subsets of CD4+ helper T-lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for better understanding and improved management of the graft-versus-host reaction. It should allow improved prevention and treatment of graft-versus-host disease and the development of new strategies to enhance a graft-versus-leukemic relapse after transplantation.

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