Effects of bilateral lung volume reduction surgery in a patient with severe pulmonary emphysema
Fujimoto, K.; Suzawa, M.; Hanaoka, M.; Matsuzawa, Y.; Kubo, K.; Sekiguchi, M.; Hanyuda, M.
Nihon Kyobu Shikkan Gakkai Zasshi 35(3): 357-364
1997
ISSN/ISBN: 0301-1542 PMID: 9168656 Document Number: 477757
A 61-year-old man suffering from severe pulmonary emphysema underwent lung volume reduction surgery on both upper lobes. By one year after surgery functional residual capacity had decreased by 2.5 L and FEV1 had increased by a factor of 2.4. Diaphragm excursion, as assessed by dynamic magnetic resonance imaging, had increased and ventilation and pulmonary gas exchange had improved. Performance on a 6-minute-walk test and exercise tolerance measured on a bicycle ergometer improved, and both peak VE and VO2 increased. Before surgery, pulmonary artery pressure Ppa and pulmonary capillary wedge pressure Pewp during exercise were abnormally high, but 6 months after the operation the increases in Ppa and Pcwp during exercise were markedly reduced.