Radiofrequency ablation in surgery
Patterson, E.J.; Scudamore, C.H.; Buczkowski, A.K.; Owen, D.A.; Nagy, A.G.
Surgical Technology International 6: 69-75
1997
ISSN/ISBN: 1090-3941 PMID: 16160957 Document Number: 477619
Recently, hyperthermia has been employed clinically as one of a variety of multimodal therapies for cancer. Hyperthermia has been applied locally, regionally, and systemically to various tumors. Local or regional hyperthermia has the advantage that a localized tumor can be heated to temperatures higher than 420 C, the maximum for total-body hyperthermia. There is mounting evidence to support a hypothesis that cancer cells are more selectively sensitive to heat than are normal cells, due to the poor blood supply of neoplastic tissue and the decreased vasodilatation capacity of the neovascular bed.