Effects of hormone replacement treatment of menopause on the risk of venous thromboembolic disease
Thery, C.; Prat, A.; Asseman, P.; Bauchart, J.J.; Michon, P.; Lesenne, M.; Jude, B.
Therapie 52(3): 165-168
1997
ISSN/ISBN: 0040-5957 PMID: 9366099 Document Number: 477215
Post-menopausal hormone replacement therapy increases the risk of venous thrombo-embolism 2- to 4-fold. The risk is highest in the beginning of the exposure to hormones and disappears rapidly after interruption of treatment. However, the increased risk remains low in absolute value and has to be weighed against coronary artery disease and post-menopausal osteoporosis.