The use of sirdalud in painful muscle tonic syndromes
Damulin, I.V.
Terapevticheskii Arkhiv 69(10): 68-72
1997
ISSN/ISBN: 0040-3660 PMID: 9471796 Document Number: 477145
The paper considers mechanisms of action and clinical efficacy of the drug sirdalud (tizanidine) in painful musculotonic syndromes. Sirdalud is an agonist of alpha 2-adrenergic receptors effective in painful musculotonic syndromes and spasticity of various genesis. The drug exhibits myorelaxative and direct central analgetic effects, is well tolerated and has minimal side effects (drowsiness). The response can be seen as early as the first treatment days. Sirdalud is applicable as alone and in combination with non-steroid anti-inflammatory drugs.